These Greek Ground Turkey Lettuce Wraps with Tzatziki are everything you need in a light yet satisfying meal. Tender, well-seasoned ground turkey is tucked into crisp lettuce leaves and topped with refreshing cucumber, tomato, and a creamy dollop of homemade tzatziki. It’s a flavor-packed, low-carb dinner idea that’s perfect for busy weeknights, meal prep, or even as a healthy party appetizer.

Table of Contents
Why I Love This Recipe
Whenever I’m craving something fresh but still hearty, this recipe is my go-to. I discovered it during a summer trip to the farmers’ market, where the cucumbers and tomatoes were practically begging to be made into tzatziki and a Greek-inspired topping. Much like my Asian Ground Turkey Stir Fry, it offers a quick, protein-packed meal, but this one feels like a Mediterranean vacation in every bite.
Fresh and flavorful
The combination of oregano-spiced turkey, crunchy vegetables, and creamy yogurt sauce is a flavor explosion without being heavy. It’s the kind of meal you can eat and still feel light and energized afterward.
Low-carb but filling
Swapping bread for lettuce makes this dish low-carb, while lean turkey and Greek yogurt provide the protein needed to keep you satisfied—similar to the balanced nutrition in my Ground Turkey Sweet Potato Meal Prep Bowls.
Ingredients You’ll Need

- Ground turkey – Lean, juicy, and perfect for absorbing Greek seasonings.
- Olive oil – Adds richness and helps the turkey brown.
- Garlic & onion – Build the savory base.
- Dried oregano & ground cumin – Classic Greek spices for warmth and depth.
- Salt & pepper – To bring out all the flavors.
- Romaine or butter lettuce leaves – Crisp and sturdy for wrapping.
- Cherry tomatoes – Fresh and sweet.
- Cucumber – Adds cool crunch.
- Tzatziki sauce – Creamy yogurt-based sauce with cucumber, garlic, and dill.
- Lemon juice – Brightens the flavor.
How to Make Greek Ground Turkey Lettuce Wraps with Tzatziki
1. Make the tzatziki
In a bowl, combine 1 cup Greek yogurt, 1/2 cup grated cucumber (squeezed dry), 1 minced garlic clove, 1 tbsp chopped fresh dill, 1 tbsp lemon juice, and a pinch of salt. Stir well and refrigerate until ready to serve.
2. Cook the turkey
Heat 1 tbsp olive oil in a skillet over medium heat. Add 1/2 diced onion and sauté for 2–3 minutes until softened. Add 1 lb ground turkey, breaking it apart with a spoon. Cook for 6–7 minutes until browned.
3. Season the turkey
Stir in 2 minced garlic cloves, 1 tsp dried oregano, 1/2 tsp ground cumin, 1/2 tsp salt, and 1/4 tsp pepper. Cook for another 2–3 minutes, allowing the spices to bloom and the turkey to absorb the flavors.
4. Prep the veggies
Dice 1 cup cherry tomatoes and 1/2 cucumber into small pieces. Keep them chilled until serving.
5. Assemble the wraps
Lay out lettuce leaves. Spoon in the turkey mixture, top with tomatoes and cucumber, then add a dollop of tzatziki. Serve immediately with lemon wedges for squeezing over the top.
Print
Greek Ground Turkey Lettuce Wraps with Tzatziki
- Total Time: 30 minutes
- Yield: 4 servings
Description
These Greek Ground Turkey Lettuce Wraps with Tzatziki are a fresh, low-carb meal featuring seasoned turkey, crisp lettuce, and creamy tzatziki sauce. Perfect for a healthy dinner or light lunch.
Ingredients
1 lb ground turkey
1 tbsp olive oil
1/2 medium onion, diced
2 garlic cloves, minced
1 tsp dried oregano
1/2 tsp ground cumin
1/2 tsp salt
1/4 tsp black pepper
1 cup cherry tomatoes, diced
1/2 cucumber, diced
8–10 romaine or butter lettuce leaves
1 cup Greek yogurt
1/2 cup grated cucumber (squeezed dry)
1 garlic clove, minced
1 tbsp fresh dill, chopped
1 tbsp lemon juice
Pinch of salt
Instructions
1. Make tzatziki: In a bowl, mix Greek yogurt, grated cucumber, garlic, dill, lemon juice, and salt. Stir well and refrigerate until serving.
2. Heat olive oil in a skillet over medium heat. Add onion and cook 2–3 minutes until softened.
3. Add ground turkey to skillet, breaking it apart with a spoon. Cook 6–7 minutes until browned.
4. Stir in minced garlic, oregano, cumin, salt, and pepper. Cook 2–3 minutes until fragrant and turkey is cooked through.
5. Prep tomatoes and cucumber, keeping them chilled until ready to serve.
6. Lay out lettuce leaves. Spoon in turkey mixture, top with tomatoes, cucumber, and a dollop of tzatziki.
7. Serve immediately with lemon wedges if desired.
Notes
Store turkey and tzatziki separately for meal prep; assemble wraps just before eating.
Add crumbled feta or olives for more Mediterranean flavor.
Use dairy-free yogurt for a dairy-free option.
- Prep Time: 15 minutes
- Cook Time: 15 minutes
- Category: Dinner
- Method: Stovetop
- Cuisine: Mediterranean
Nutrition
- Serving Size: 2 wraps
- Calories: 310
- Sugar: 4g
- Sodium: 420mg
- Fat: 17g
- Saturated Fat: 4g
- Unsaturated Fat: 10g
- Trans Fat: 0g
- Carbohydrates: 8g
- Fiber: 2g
- Protein: 28g
- Cholesterol: 75mg
Keywords: Greek Ground Turkey Lettuce Wraps, Low Carb Turkey Wraps, Healthy Turkey Lettuce Wraps, Tzatziki Wraps
Pro Tips for the Best Lettuce Wraps
- Use sturdy lettuce like romaine hearts or butter lettuce to prevent tearing.
- Squeeze excess liquid from cucumber before adding to tzatziki to keep it creamy.
- Make the turkey mixture ahead and store separately from lettuce for easy meal prep.
- For extra tang, add crumbled feta on top.
Variations
Make it spicy
Add a pinch of red pepper flakes to the turkey while cooking for a little heat.
Change the protein
Ground chicken or even lamb work beautifully in this recipe.
Dairy-free
Use a dairy-free yogurt for the tzatziki to make the wraps dairy-free.
Serving Suggestions
These wraps pair perfectly with a side of roasted vegetables, a quinoa salad, or some warm pita bread if you want to add carbs back in.
Nutrition Snapshot
Nutrient | Per Serving |
---|---|
Calories | 310 |
Protein | 28g |
Carbohydrates | 8g |
Fiber | 2g |
Fat | 17g |
FAQ – Greek Ground Turkey Lettuce Wraps
Can I make these ahead?
Yes, cook the turkey and prep the tzatziki ahead, but store separately. Assemble just before serving for best texture.
What lettuce works best?
Romaine hearts and butter lettuce are both sturdy and flexible enough to hold the filling.
How long does the turkey mixture last?
Store in an airtight container in the fridge for up to 3 days.
Conclusion
These Greek Ground Turkey Lettuce Wraps with Tzatziki are a fresh, flavorful, and healthy way to enjoy Mediterranean flavors without the heaviness of bread. They’re quick to make, customizable, and perfect for both weekday meals and entertaining guests.